May 23, 2024
Health News

Metformin Introducing In People With Bipolar Shows Weight Loss


Have you ever heard about the drug that is best for diabetics causing weight loss? Yes you have heard me right. So taking the medication metformin can help reduce weight in people who are on bipolar drugs as per the new research. Yes it is the great invention in the health domain. The metformin lower the weight but how?  and what is its goal? Here Doctors advice the drug metformin for type 2 diabetes. Many reports and research have been made on this drug to find how metformin affects weight. Not only does it support in weight loss in people who use drugs for bipolar issues but it also helps people who never use drugs for bipolar disorder. When it comes to weight loss the metformin shows remarkable results.

What is Metformin?

What is this med? It is the med that doctors give to treat type 2 diabetes and PCOS OR  polycystic ovary syndrome. It is the first line of therapy for people with two diabetes who are obese or overweight. It works by assisting the body in keeping fitness and lowering the level of sugar that the liver produces. So the drug  metformin is normally a safe drug but it can cause notable side effects like stomach upset, diarrhoea and vomiting. These effects are usually linked with their own but the metformin can result in serious side effects such as lactic acidosis. Lactic acidosis is the lactic acid buildup in one blood and it can be lethal.

So metformin is generally safe for most people but it is vital to talk to the doctor before taking it. Specifically if one has kidney issues, liver concerns or CVS. To make it clear to you we have made the list of key points.

for more understanding, you can also watch this video :

Here are the top key points about the metformin

  • It is a 1st-line treatment for type 2 diabetes in individuals who are overweight or obese.
  • Doctore prescribes it to treat polycystic ovary syndrome or PCOS.
  • It works by allowing the body to utilize insulin effectively and by lowering the amount of sugar made by the liver.
  • It is a fairly safe drug but it can cause side effects like nausea, diarrhoeaand stomach upset.
  • Hence it is vital to talk to the doctor before taking metformin specifically if one has kidney concerns, liver issues or heart disease.

How Metformin Reduce Weight

Now you have heard about the metformin. What is its usage and side effect? But the main query is how does it reduce the weight?

Metformin can reduce weight in several ways such as 

Lowering appetite

 Metformin can improve leptin production in the body. It is a hormone that makes one feel full. So it can also decrease the production of ghrelin a hormone that makes one feel hungry.

Boosting blood sugar control

Metformin can permit the body to utilise insulin which can lead to lower blood sugar levels. So high blood sugar levels can lead to raised hunger and weight gain.

Reducing the release of glucose by the liver

The liver makes glucose and it is the main source of energy for the body. Metformin can lower the level of glucose that the liver makes. Hence it can lead to weight loss.

Changing the gut microbes

The gut bacteria and it is bacteria that live in our gut. Here Metformin can change the gut microbes which may lead to weight loss.

Causing side effects that lower appetite

Some side effects of metformin like nausea and diarrhoea can lower appetite.

Now is the time to learn about how it reduces weight in the patient who is taking drugs for bipolar.

Bipolar Drugs

Bipolar Disorder

For bipolar disorder doctors prescribe second-generation antipsychotic medications (SGAs). These drugs improve mental health with adverse side effects like high blood pressure and blood pressure. They can also notice an increase in their appetite hence weight gain. As per Dr. Victor Fornari they are working to improve mental health so please deal with the weight gain issues. He also states that many patients stop taking the drug because of the weight gain. They do not want to gain weight when taking any psychotic drugs.

Patients Want Less Side Effects: the Study Metformin and Weight Loss

As per the study the patient wants drugs that have fewer side effects and hence no weight gain.  The research had broad signup bars and was performed at various hospitals she stated. It had more than 1500 people ages 8 to 19 who had bipolar illness and were taking the SGAs. She added that it was a big sample of patients to truly explain what was going on. She said she did not know that anybody had ever done an analysis of this magnitude.

Prescribed Metformin

Trial parties received advice for exercise and healthy eating. And they also prescribed metformin to half of the participants.

She stated that If patients were not doing great on the metformin they might come off and remain in this analysis.  Further she added that they are just testing to fulfil the patients where and when they get services and seeing what occurs to them over the time of two years.

In a study before the interventions about 87% of youth said taking their bipolar medicine daily but most were low with the weight. The study team also gathered data to find if young persons had metabolic syndrome. What is this? It is a chance for  CVS and diabetes se which is a common effect of taking SGAs. At the beginning around 33% had this metabolic syndrome. The key features of metabolic syndrome consist of the following:

  • obesity
  • high blood pressure
  • high triglycerides 
  •  elevated glucose 

  So it is vital that clinicians scan for metabolic syndrome when dealing with youth with 2nd-generation antipsychotics.

Out Come Of Study About Metformin and Weight Loss

6-month follow-up Study revealed that metformin had a subtle but powerful effect in controlling and in a few cases changing weight gain. So it was secure with some GIT symptoms as the just side effect.

  It is not a drug one takes and weight falls off of them but it manages to lessen that out-of-control hunger. So we think then creates it more effortless for a person to stick to a nutritious diet and as they shed some weight possibly make it simple for them to do more exercise. Jeffrey Welge professor at the University of Cincinnati stated this. So the lifestyle is what is driving promising outcomes but metformin is some points putting the breeze at the back to assist with that Welge stated. So taking metformin never has a noticeable impact on metabolic syndrome in the brief term. For this we need more study on that investigators said.


It is safe,  useful and very affordable. It is one of the interventions that has the possibility to keep widespread relevance as per DR. Fornari. Further added that it is not a drug that one needs to have the endocrinologist or a paediatrician suggest and we think it actually tells to the point that the psychiatrist ought to be watching for the whole person the mental and physical health of the person.

1 Comment

  • Katharina January 3, 2024

    What’s Going down i am new to this, I stumbled upon this I have found It absolutely helpful and it has
    aided me out loads. I’m hoping to contribute & aid different users like its helped me.
    Good job.

Leave a Reply

Your email address will not be published. Required fields are marked *